In a three-minute video posted to X, Netanyahu accuses the leaders of Iran of making speeches about defending Gaza and Lebanon but that "every day that regime plunges our region deeper into darkness and deeper into war".
"There is nowhere in the Middle East Israel cannot reach, there is nowhere we will not go to protect our people and protect our country," he says.
"With every passing moment, the regime is bringing you, the noble Persian people, closer to the abyss," he says.
Netanyahu says that when Iran is "finally free" – saying that moment will come "a lot sooner than people think" – then everything will be different and the two nations will be at peace.
"Iran will thrive as never before," he says, adding: "Don't let a small group of fanatic theocrats crush your hopes and your dreams. You deserve better."